Effects of RNA interference-mediated silencing of gamma-secretase complex components on cell sensitivity to caspase-3 activation.
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Overview
publication date
- June 7, 2004
published in
has subject area
- Amyloid Precursor Protein Secretases
- Animals
- Apoptosis
- Aspartic Acid Endopeptidases
- Blotting, Western
- Caspase 3
- Caspases
- Cell Line, Tumor
- Endopeptidases
- Enzyme Activation
- Exons
- Gene Deletion
- Gene Silencing
- Humans
- Membrane Glycoproteins
- Membrane Proteins
- Mice
- Mice, Transgenic
- Mutation
- Peptide Hydrolases
- Presenilin-1
- Protein Structure, Tertiary
- RNA Interference
- RNA, Small Interfering