RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.
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Overview
publication date
- February 7, 2005
published in
has subject area
- Adaptor Proteins, Signal Transducing
- Amino Acid Motifs
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Blotting, Western
- Cadherins
- Carrier Proteins
- Cell Line, Tumor
- Electroporation
- Enzyme-Linked Immunosorbent Assay
- Gene Silencing
- Humans
- Nerve Tissue Proteins
- Protein Binding
- RNA Interference
- RNA, Small Interfering
- Time Factors
- Transfection