authors
- Tash, Joseph S
- Kinzy, Terri Goss
- Blagg, Brian S J
- Georg, Gunda I
- Chakrasali, Ramappa
- Jakkaraj, Sudhakar R
- Hughes, Jennifer
- S. Kendall Smith, MD, PhD
- Hornbaker, Kaori
- Heckert, Leslie L
- Ozturk, Sedide B
- Hadden, M Kyle
Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and stimulates Il1a transcription in rat Sertoli cells.
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Overview
publication date
- January 1, 2008
published in
- Biology of reproduction Journal
has subject area
- Administration, Oral
- Amino Acid Sequence
- Animals
- Binding Sites
- Cell Line
- Cell Line, Tumor
- Female
- HSP90 Heat-Shock Proteins
- Indazoles
- Interleukin-1alpha
- Male
- Models, Biological
- Molecular Sequence Data
- Ovarian Neoplasms
- Peptide Elongation Factor 1
- Rats
- Sertoli Cells
- Spermatogenesis-Blocking Agents
- Testis
- Transcription, Genetic