authors
- Vermulst, Marc
- Jonathan Wanagat, MD, PhD
- Kujoth, Gregory C
- Bielas, Jason H
- Rabinovitch, Peter S
- Prolla, Tomas A
- Loeb, Lawrence A
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.
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- Identity
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Overview
publication date
- March 2, 2008
published in
- Nature genetics Journal
has subject area
- Aging, Premature
- Animals
- Base Sequence
- Catalase
- DNA Polymerase gamma
- DNA Repair
- DNA, Mitochondrial
- DNA-Directed DNA Polymerase
- Electron Transport Complex IV
- Mice
- Mice, Knockout
- Mice, Transgenic
- Molecular Sequence Data
- Mutagenesis
- Oxidative Stress
- Phenotype
- Point Mutation
- Sequence Deletion
- Sequence Homology, Nucleic Acid
- Tissue Distribution