Keywords 99-residue membrane-associated C-terminus fragment AD AICD APH-1 APP APP-C83 APP-C99 APP-CTF APP-c-terminal fragment ATP Adenosine-5'-triphosphate Alzheimer's disease Aβ BACE BACE cleavage of APP CAD DAPT General anesthetics IDE Insulin degrading enzyme N-[N-(3,5-difluorophenacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester Neurotoxicity PEN-2 TNF-α WT Z-VAD amyloid precursor protein anterior pharynx-defective 1 carbobenzoxy-valyl -alanyl-aspartyl-[Omethyl]- fluromethylketone carboxyl-terminus fragment of 83 amino acids coronary artery disease presenilin enhancer 2 tumor necrosis factor-α wild-type α-APPs α-secretase cleavage of APP β-APPs β-Amyloid protein β-amyloid precursor protein intracellular domain β-amyloid protein β-site APP-cleaving enzyme