authors
- Rao, Feng
- Barrow, Roxanne
- Wu, Mingxuan
- Fiedler, Dorothea
- Barrow, James C
- Snyder, Solomon H
- Cha, Jiyoung
- Xu, Jing
- Xu, Risheng
- Matthew S. Vandiver MD, PhD
- Tyagi, Richa
- Tokhunts, Robert
- Koldobskiy, Michael A
- Fu, Chenglai
Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.
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Overview
publication date
- March 20, 2014
published in
- Molecular cell Journal
has subject area
- Animals
- Apoptosis
- Ataxia Telangiectasia Mutated Proteins
- B-Lymphocytes
- Binding Sites
- Carrier Proteins
- Casein Kinase II
- DNA-Activated Protein Kinase
- DNA-Binding Proteins
- Enzyme Stability
- HCT116 Cells
- HEK293 Cells
- Humans
- Inositol Phosphates
- Intracellular Signaling Peptides and Proteins
- Mice, Knockout
- Neoplasms
- Nuclear Proteins
- Phosphorylation
- Phosphotransferases (Phosphate Group Acceptor)
- Proto-Oncogene Proteins c-ets
- RNA Interference
- Serine
- Signal Transduction
- Telomere-Binding Proteins
- Transfection
- Tumor Suppressor Protein p53