authors
- Paul, Bindu D
- Sbodio, Juan I
- Xu, Risheng
- Matthew S. Vandiver MD, PhD
- Cha, Jiyoung Y
- Snowman, Adele M
- Snyder, Solomon H
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease.
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Overview
publication date
- March 26, 2014
published in
- Nature Journal
has subject area
- Animals
- Brain
- Corpus Striatum
- Cystathionine gamma-Lyase
- Cysteine
- Dietary Supplements
- Disease Models, Animal
- Drinking Water
- Gene Deletion
- Gene Expression Regulation, Enzymologic
- Huntingtin Protein
- Huntington Disease
- Male
- Mice
- Mutant Proteins
- Nerve Tissue Proteins
- Neuroprotective Agents
- Oxidative Stress
- Sp1 Transcription Factor
- Transcription, Genetic