authors
- Velez de Mendizabal, Nieves
- Jackson, Kimberley
- Eastwood, Brian
- Swanson, Steven
- Bender, David M
- Lowe, Stephen
- Bies, Robert R
A population PK model for citalopram and its major metabolite, N-desmethyl citalopram, in rats.
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Overview
publication date
- January 1, 2015
published in
has subject area
- Administration, Intravenous
- Administration, Oral
- Animals
- Antidepressive Agents, Second-Generation
- Area Under Curve
- Biological Availability
- Biotransformation
- Citalopram
- Computer Simulation
- Linear Models
- Male
- Metabolic Clearance Rate
- Models, Animal
- Models, Biological
- Models, Statistical
- Monte Carlo Method
- Nonlinear Dynamics
- Rats, Sprague-Dawley
- Rats, Wistar
- Selective Serotonin Reuptake Inhibitors
- Species Specificity