authors
- Kowalsky, Allison Ho
- Namkoong, Sim
- Mettetal, Eric
- Park, Hwan-Woo
- Kazyken, Dubek
- Fingar, Diane C
- Lee, Jun Hee
The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation.
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Overview
publication date
- January 8, 2020
published in
has subject area
- Animals
- Diet, High-Fat
- Gene Expression Regulation
- Hep G2 Cells
- Humans
- Insulin
- Insulin Resistance
- Mechanistic Target of Rapamycin Complex 2
- Mice
- Multiprotein Complexes
- Obesity
- Peroxidases
- Phosphatidylinositol 3-Kinases
- Phosphorylation
- Protein Binding
- Proteins
- Proto-Oncogene Proteins c-akt
- Signal Transduction
- TOR Serine-Threonine Kinases