authors
- Xie, Sai-Sai
- Cheng, Maojun
- Tang, Weizhong
- Liang, Ningsheng
- Jiang, Neng
- Liu, Jing
- Tang, Chunli
- Pang, Chengyun
- Li, Qing
- Qin, Yuelian
- Nong, Xiaojie
- Zhang, Zhipeng
Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer's disease.
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Overview
publication date
- January 1, 2020
published in
has subject area
- Alzheimer Disease
- Amyloid beta-Peptides
- Animals
- Cell Line, Tumor
- Cell Survival
- Clorgyline
- Dose-Response Relationship, Drug
- Drug Design
- Humans
- Indans
- Male
- Models, Molecular
- Molecular Structure
- Monoamine Oxidase
- Monoamine Oxidase Inhibitors
- Neuroprotective Agents
- Peptide Fragments
- Protein Aggregates
- Rats
- Rats, Sprague-Dawley
- Structure-Activity Relationship