Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway.
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Overview
publication date
- January 1, 2021
published in
- Molecular immunology Journal
has subject area
- Alkaloids
- Animals
- Arthritis, Experimental
- Basic Helix-Loop-Helix Transcription Factors
- Cells, Cultured
- Collagen
- Human Umbilical Vein Endothelial Cells
- Humans
- Male
- Matrines
- Neovascularization, Pathologic
- Phosphatidylinositol 3-Kinases
- Proto-Oncogene Proteins c-akt
- Quinolizines
- Rats
- Rats, Sprague-Dawley
- Ribonuclease, Pancreatic
- Signal Transduction
- Synovial Membrane
- Synoviocytes
- Vascular Endothelial Growth Factor A