authors
- Liu, Jing
- Cheng, Maojun
- Liu, Peng
- Cao, Duanyuan
- Luo, Jinchong
- Wan, Yang
- Fang, Yuanying
- Jin, Yi
- Xie, Sai-Sai
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
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Overview
publication date
- January 1, 2022
published in
has subject area
- Acetylcholinesterase
- Alzheimer Disease
- Amyloid beta-Peptides
- Animals
- Cholinesterase Inhibitors
- Cyclooxygenase 2
- Dimethyl Fumarate
- Hydrogen Peroxide
- Interleukin-6
- Ligands
- Mice
- Molecular Docking Simulation
- NF-E2-Related Factor 2
- Reactive Oxygen Species
- Scopolamine
- Tumor Necrosis Factor-alpha
- ortho-Aminobenzoates