The lifespan-extending MEK1 inhibitor trametinib promotes regulation of de novo lipogenesis enzymes by chaperone-mediated autophagy. uri icon

authors

  • Chen, Jiexian
  • Berg, Joshua
  • Burns, Calvin M
  • Jia, Hanyi
  • Li, Xinna
  • Miller, Richard A
  • Endicott, S Joseph
  • Garcia, Gonzalo

publication date

  • June 25, 2025