authors

• Dodge, Hiroko H
• Chen, Liu
• Wu, Chao-Yi
• Cutter, Gary
• Bowman, Gene L
• Feldman, Howard H
• Arnold, Steven E

publication date

• October 2025

published in

• Alzheimer's & dementia : the journal of the Alzheimer's Association  Journal

has subject area

• Alzheimer Disease
• Biomarkers
• Clinical Trials as Topic
• Computer Simulation
• Humans
• Research Design

Keywords

• Single‐arm Lead‐In with Multiple measures (SLIM)
• between‐individual variability
• clinical trial
• plasma biomarkers
• statistical power
• within‐individual variability

Digital Object Identifier (DOI)

• https://doi.org/10.1002/alz.70787

PubMed ID

• 41122812

start page

end page

volume

• 21

issue

• 10