Therapeutic effect of an MRGPRX2/MRGPRB2 antagonist on LL-37-induced rosacea-like inflammation in mice.
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Overview
publication date
- November 26, 2025
published in
has subject area
- Animals
- Anti-Inflammatory Agents
- Antimicrobial Cationic Peptides
- Cathelicidins
- Cell Degranulation
- Chemokine CCL2
- Disease Models, Animal
- Humans
- Inflammation
- Keratinocytes
- Macrophages
- Male
- Mast Cells
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nerve Tissue Proteins
- Pruritus
- Receptors, G-Protein-Coupled
- Receptors, Neuropeptide
- Rosacea
- Skin