A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia. uri icon

authors

  • Mirfakhar, Farzaneh S
  • Macauley, Shannon L
  • Karch, Celeste M
  • Marsh, Jacob A
  • Sato, Chihiro
  • Schache, Kylie J
  • Minaya, Miguel A
  • Dolle, Roland E
  • Pak, Stephen C
  • Silverman, Gary A
  • Perlmutter, David H

publication date

  • March 31, 2026