Lysosomal dysfunction drives a transcriptional and epigenetic signature found in disease-associated microglia in neurodegenerative diseases. uri icon

authors

  • Balak, Christopher D
  • Saisan, Payam
  • Sarsani, Vishal
  • Kleemann, Kilian L
  • Zhang, Xiaoming
  • Pasillas, Martina P
  • O'Brien, Sydney
  • Bokor, Juliette A
  • Gordts, Philip L S M
  • Butovsky, Oleg
  • Stevens, Beth
  • Schlachetzki, Johannes C M
  • Kamme, Fredrik
  • Glass, Christopher K
  • Lana, Addison J
  • West, Elizabeth
  • Hong, Christine
  • DuGal, Jordan
  • Zhou, Yi
  • Li, Benjamin
  • Spann, Nathanael J

publication date

  • August 3, 2026