Training Program for Antiretroviral Discovery, Evaluation and Application Research (ADEAR)
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PROJECT SUMMARY The Training Program for Antiretroviral Discovery, Evaluation and Application Research (ADEAR) is an integrative program that provides multidisciplinary training in basic/translational, clinical, health services, and dissemination/implementation science in HIV. Postdoctoral scientists receive training under the direction under faculty at the University of Colorado, Colorado State University and the University of Denver who are who experienced mentors and actively engaged in research related to the discovery and evaluation of new antiretroviral drugs, application of existing antiretrovirals, and strategies to improve delivery for the treatment and prevention of HIV. This renewal application for T32 funding will provide ongoing support for our highly successful ADEAR research training program. To foster multidisciplinary research opportunities for ADEAR trainees, the program has engaged Core Faculty Mentors, experienced and productive HIV/AIDS investigators, Co-Mentors, and Content Experts who bring unique complementary expertise, ensuring an exceptional training experiences. In addition to didactic training, mentored training for trainees can include antiretroviral discovery through basic and translational science, clinical evaluation of antiretrovirals, and application/delivery of antiretrovirals in clinical and community settings. The program includes the following innovative features: • Kristine Erlandson, M.D., a clinical investigator and K24-funded mentor; Mamuka Kvaratskhelia, Ph.D., a basic scientist and mentor; and Joshua Barocas, M.D., a health services investigator and mentor will serve as Co-Program Directors. • Integrated training pathways for HIV basic/translational, clinical, health services, and dissemination/ implementation science will better meet the needs of 1) trainees with different research backgrounds and career paths and 2) the HIV epidemic, supporting development of novel therapies and delivery strategies to ensure therapies can be implemented in the populations at greatest risk. • A robust plan to facilitate recruitment of trainees both from within the affiliated institutions and from other institutions outside of Colorado. • Measures to facilitate trainee careers as NIH funded independent investigators and a formal plan to improve the mentoring skills of program faculty. • Robust methods for internal and external review of program progress and procedures for adjusting the training curriculum, if necessary, to better meet the needs of trainees. Renewal of this highly successful postdoctoral training program will ensure the ongoing training of scientists from different disciplines, preparing trainees for collaborative research careers, and the skills needed to fill knowledge gaps in the use of antiretrovirals as tools to end the HIV epidemic.
