Interdisciplinary Cardiovascular Research Training Program
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PROJECT SUMMARY/ABSTRACT Cardiovascular disease continues to be a dominant cause of morbidity and mortality in the United States and throughout the world. While many gains have been achieved in some areas, the epidemic of obesity, diabetes, and sedentary lifestyles is contributing to a reversal of these trends. The advances made have resulted from the dedication and talents of many researchers in basic, translational, clinical, and population epidemiological scientific inquiry. For nearly 50 years, the Johns Hopkins T32 Program in Cardiovascular Disease has trained many of these researchers, and with this renewal proposal we aim to continue this success. Our philosophy is to provide a broad-based, multi- and inter-disciplinary research environment with which to train post-doctoral fellows in basic, translational, clinical, and/or population science. Our T32 program includes individuals with MD, MD PhD, and PhD degrees, adapting to an evolving research environment that requires a wider breadth of backgrounds and experience to pursue different types of research. This provides a unique integrative environment for our T32 program to engage in interdisciplinary training, melding clinical insights, skills, and research with basic molecular and cellular biology researchers. While centered in the Division of Cardiology, the program engages faculty throughout the Johns Hopkins Medical Institutions with expertise and interest in cardiovascular research. This includes faculty in Divisions/Departments of Pulmonary Medicine, Epidemiology, Pathology, Biomedical Engineering, Computer Science, Surgery, Neuroscience, and Genetic Medicine. All have long-standing collaborations with Cardiology Division faculty. The primary areas of research covered in our program encompass basic science in ventricular and vascular pathobiology, pulmonary hypertension; regenerative cell biology and tissue engineering; immunology and metabolism; computational modeling, and bioinformatics including artificial intelligence and deep learning. Clinical and translational research focuses on heart failure, electrophysiology, women’s cardiovascular health, disparities, and cardiovascular imaging. Large population studies focus on preventive cardiology, risk prediction, and genomics/omics. The program supports 12 positions for generally 2 years of research training. It also includes two positions with a structured year of formal course work to provide a Master’s degree in Clinical Investigation or in Biomedical Informatics and Data Science in Healthcare. With this renewal, we continue our primary goal of providing leadership in academic cardiology, training future leaders in all levels of research to help combat cardiovascular disease.
