Acta neuropathologica Journal

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Overview

publication venue for

• Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord..  150:-. 2025
• Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease..  149:-. 2025
• Elevated expression of the retrotransposon LINE-1 drives Alzheimer's disease-associated microglial dysfunction..  148:-. 2024
• Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups..  148:-. 2024
• Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease..  148:-. 2024
• Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer's Coordinating Center database..  147:-. 2024
• Neuropathological findings in Down syndrome, Alzheimer's disease and control patients with and without SARS-COV-2: preliminary findings..  147:-. 2024
• Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease..  147:-. 2024
• Disentangling and quantifying the relative cognitive impact of concurrent mixed neurodegenerative pathologies..  147:-. 2024
• Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study..  147:-. 2023
• Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation..  145:749-772. 2023
• LATE-NC staging in routine neuropathologic diagnosis: an update..  145:159-173. 2022
• Tuberous sclerosis complex is associated with a novel human tauopathy..  145:1-12. 2022
• RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation..  145:29-48. 2022
• Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo..  144:881-910. 2022
• Neuropathologic scales of cerebrovascular disease associated with diffusion changes on MRI..  144:1117-1125. 2022
• Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts..  144:27-44. 2022
• Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice..  143:663-685. 2022
• Correction to: Apolipoprotein E regulates lipid metabolism and α‑synuclein pathology in human iPSC‑derived cerebral organoids..  143:119-121. 2022
• Genome-wide association study and functional validation implicates JADE1 in tauopathy..  143:33-53. 2021
• Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids..  142:807-825. 2021
• Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease..  142:689-706. 2021
• Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607..  141:697-708. 2021
• Latent trait modeling of tau neuropathology in progressive supranuclear palsy..  141:667-680. 2021
• Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population..  141:623-624. 2021
• Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions..  141:359-381. 2021
• The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer's disease..  141:631-650. 2021
• Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy..  140:659-674. 2020
• TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis..  140:513-534. 2020
• Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity..  139:959-962. 2020
• Overlapping genetic architecture between Parkinson disease and melanoma..  139:347-364. 2019
• The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion..  139:45-61. 2019
• C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy..  138:795-811. 2019
• A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity..  138:237-250. 2019
• Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes..  138:167-169. 2019
• Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD..  137:879-899. 2019
• Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease..  137:209-226. 2018
• Rebuttal to Drs. Grinberg and Heinsen..  136:-. 2018
• Sex and age interact to determine clinicopathologic differences in Alzheimer's disease..  136:873-885. 2018
• Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease..  136:919-938. 2018
• Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy..  136:709-727. 2018
• Sex-specific genetic predictors of Alzheimer's disease biomarkers..  136:857-872. 2018
• Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients..  136:425-443. 2018
• Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits..  134:749-767. 2017
• [F-18]-AV-1451 binding correlates with postmortem neurofibrillary tangle Braak staging..  134:619-628. 2017
• Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers..  133:839-856. 2017
• Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART)..  133:705-715. 2017
• Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci..  132:197-211. 2016
• Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status..  131:925-33. 2016
• Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission..  130:303-5. 2015
• Primary age-related tauopathy (PART): a common pathology associated with human aging..  128:755-66. 2014
• Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice..  127:645-65. 2014
• TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions..  127:407-18. 2014
• Anti-Aβ antibody target engagement: commentary regarding Watt et al. Acta Neuropathol 127:803-810 (2014)..  128:609-10. 2014
• Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy..  126:39-50. 2013
• Alzheimer's pathogenesis: is there neuron-to-neuron propagation?.  121:589-95. 2011
• Morphometry of the human substantia nigra in ageing and Parkinson's disease..  115:461-70. 2008
• Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration..  114:5-22. 2007
• Entorhinal cortex of aged subjects with Down's syndrome shows severe neuronal loss caused by neurofibrillary pathology..  97:156-64. 1999

Identity

International Standard Serial Number (ISSN)

• 0001-6322
• 1432-0533