Nature communications Journal

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Overview

publication venue for

• Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer's disease..  16:-. 2025
• Integrated multiomics of pressure overload in the human heart prioritizes targets relevant to heart failure..  16:-. 2025
• AI-guided patient stratification improves outcomes and efficiency in the AMARANTH Alzheimer's Disease clinical trial..  16:-. 2025
• In vivo self-renewal and expansion of quiescent stem cells from a non-human primate..  16:-. 2025
• Stabilizing brain-computer interfaces through alignment of latent dynamics..  16:-. 2025
• Dietary lipids are largely deposited in skin and rapidly affect insulating properties..  16:-. 2025
• Combination radiation and αPD-L1 enhance tumor control by stimulating CD8+ PD-1+ TCF-1+ T cells in the tumor-draining lymph node..  16:-. 2025
• Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele..  16:-. 2025
• Daytime eating during simulated night work mitigates changes in cardiovascular risk factors: secondary analyses of a randomized controlled trial..  16:-. 2025
• Floods and cause-specific mortality in the United States applying a triply robust approach..  16:-. 2025
• Epidemiology and transmission dynamics of multidrug-resistant organisms in nursing homes within the United States..  16:-. 2025
• Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1..  16:-. 2025
• Retraction Note: Kynurenine promotes neonatal heart regeneration by stimulating cardiomyocyte proliferation and cardiac angiogenesis..  16:-. 2025
• Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer's disease..  16:-. 2025
• Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients..  16:-. 2025
• Remyelination protects neurons from DLK-mediated neurodegeneration..  15:-. 2024
• Multi-parametric thrombus profiling microfluidics detects intensified biomechanical thrombogenesis associated with hypertension and aging..  15:-. 2024
• Depletion of loss-of-function germline mutations in centenarians reveals longevity genes..  15:-. 2024
• CYP1B1-RMDN2 Alzheimer's disease endophenotype locus identified for cerebral tau PET..  15:-. 2024
• PRC2-AgeIndex as a universal biomarker of aging and rejuvenation..  15:-. 2024
• Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade..  15:-. 2024
• Personalized and muscle-specific OXPHOS measurement with integrated CrCEST MRI and proton MR spectroscopy..  15:-. 2024
• Gliovascular transcriptional perturbations in Alzheimer's disease reveal molecular mechanisms of blood brain barrier dysfunction..  15:-. 2024
• Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer's disease..  15:-. 2024
• Tau propagation in the brain olfactory circuits is associated with smell perception changes in aging..  15:-. 2024
• Author Correction: FUNDC1-dependent mitochondria-associated endoplasmic reticulum membranes are involved in angiogenesis and neoangiogenesis..  15:-. 2024
• The impact of exercise on gene regulation in association with complex trait genetics..  15:-. 2024
• Dynamic interplay of microtubule and actomyosin forces drive tissue extension..  15:-. 2024
• Immunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection..  15:-. 2024
• Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia..  15:-. 2024
• Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients..  15:-. 2024
• Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications..  15:-. 2024
• Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer's disease and aging..  15:-. 2024
• IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition..  15:-. 2024
• Single-cell mapping of lipid metabolites using an infrared probe in human-derived model systems..  15:-. 2024
• Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study..  15:-. 2024
• Author Correction: The endocannabinoid N-arachidonoyl dopamine is critical for hyperalgesia induced by chronic sleep disruption..  14:-. 2023
• Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy..  14:-. 2023
• Gut microbiota impacts bone via Bacteroides vulgatus-valeric acid-related pathways..  14:-. 2023
• The endocannabinoid N-arachidonoyl dopamine is critical for hyperalgesia induced by chronic sleep disruption..  14:-. 2023
• European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation..  14:-. 2023
• De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8..  14:-. 2023
• Bacteroides Fragilis in the gut microbiomes of Alzheimer's disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice..  14:-. 2023
• Antibody-mediated NK cell activation as a correlate of immunity against influenza infection..  14:-. 2023
• Challenges in developing Geroscience trials..  14:-. 2023
• Expanded vacuum-stable gels for multiplexed high-resolution spatial histopathology..  14:-. 2023
• Mapping mechanical stress in curved epithelia of designed size and shape..  14:-. 2023
• Structural basis for DARC binding in reticulocyte invasion by Plasmodium vivax..  14:-. 2023
• Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection..  14:-. 2023
• Natural history of long-COVID in a nationwide, population cohort study..  14:-. 2023
• Stacked binding of a PET ligand to Alzheimer's tau paired helical filaments..  14:-. 2023
• Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers..  14:-. 2023
• Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells..  14:-. 2023
• Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders..  14:-. 2023
• High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform..  14:-. 2023
• Age-related matrix stiffening epigenetically regulates α-Klotho expression and compromises chondrocyte integrity..  14:-. 2023
• Kynurenine promotes neonatal heart regeneration by stimulating cardiomyocyte proliferation and cardiac angiogenesis..  13:-. 2022
• Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis..  13:-. 2022
• Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders..  13:-. 2022
• A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues..  13:-. 2022
• Author Correction: FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease..  13:-. 2022
• Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes..  13:-. 2022
• Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder..  13:-. 2022
• Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition..  13:-. 2022
• Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals..  13:-. 2022
• Heterotypic interactions drive antibody synergy against a malaria vaccine candidate..  13:-. 2022
• Cell specific peripheral immune responses predict survival in critical COVID-19 patients..  13:-. 2022
• Endothelial cell-specific expression of serine/threonine kinase 11 modulates dendritic cell differentiation..  13:-. 2022
• Characterization of the COPD alveolar niche using single-cell RNA sequencing..  13:-. 2022
• Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19..  13:-. 2022
• Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer..  12:-. 2021
• Impact of maternal antibodies and microbiota development on the immunogenicity of oral rotavirus vaccine in African, Indian, and European infants..  12:-. 2021
• Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue..  12:-. 2021
• A cross-sectional analysis of meteorological factors and SARS-CoV-2 transmission in 409 cities across 26 countries..  12:-. 2021
• An immune response characterizes early Alzheimer's disease pathology and subjective cognitive impairment in hydrocephalus biopsies..  12:-. 2021
• Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer's disease..  12:-. 2021
• A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech..  12:-. 2021
• FUNDC1-dependent mitochondria-associated endoplasmic reticulum membranes are involved in angiogenesis and neoangiogenesis..  12:-. 2021
• Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer's disease..  12:-. 2021
• Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice..  12:-. 2021
• PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2..  12:-. 2021
• Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women..  12:-. 2021
• Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains..  11:-. 2020
• Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease..  11:-. 2020
• Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals..  11:-. 2020
• Common diseases alter the physiological age-related blood microRNA profile..  11:-. 2020
• SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease..  11:-. 2020
• Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses..  11:-. 2020
• Molecular estimation of neurodegeneration pseudotime in older brains..  11:-. 2020
• APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids..  11:-. 2020
• Association of APOE e2 genotype with Alzheimer's and non-Alzheimer's neurodegenerative pathologies..  11:-. 2020
• SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood..  11:-. 2020
• Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury..  11:-. 2020
• GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer..  11:-. 2020
• Machine learning-based prediction of acute coronary syndrome using only the pre-hospital 12-lead electrocardiogram..  11:-. 2020
• A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs..  11:-. 2020
• Evolution of generalist resistance to herbicide mixtures reveals a trade-off in resistance management..  11:-. 2020
• Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells..  11:-. 2020
• Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment..  11:-. 2020
• Multiple network properties overcome random connectivity to enable stereotypic sensory responses..  11:-. 2020
• A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems..  11:-. 2020
• Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway..  11:-. 2020
• Sexual-dimorphism in human immune system aging..  11:-. 2020
• Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing..  11:-. 2020
• Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study..  11:-. 2020
• FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease..  11:-. 2020
• Epitaxial nucleation and lateral growth of high-crystalline black phosphorus films on silicon..  11:-. 2020
• Simultaneous enhanced efficiency and thermal stability in organic solar cells from a polymer acceptor additive..  11:-. 2020
• Estimating heritability and genetic correlations from large health datasets in the absence of genetic data..  10:-. 2019
• Publisher Correction: Circulating miR-103a-3p contributes to angiotensin II-induced renal inflammation and fibrosis via a SNRK/NF-κB/p65 regulatory axis..  10:-. 2019
• A novel rapamycin analog is highly selective for mTORC1 in vivo..  10:-. 2019
• Circulating miR-103a-3p contributes to angiotensin II-induced renal inflammation and fibrosis via a SNRK/NF-κB/p65 regulatory axis..  10:-. 2019
• Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity..  10:-. 2019
• Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis..  9:-. 2018
• Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration..  9:-. 2018
• A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation..  9:-. 2018
• Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation..  9:-. 2018
• APOE ε2 is associated with increased tau pathology in primary tauopathy..  9:-. 2018
• UBXN3B positively regulates STING-mediated antiviral immune responses..  9:-. 2018
• Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function..  9:-. 2018
• MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB..  9:-. 2018
• GWAS of epigenetic aging rates in blood reveals a critical role for TERT..  9:-. 2018
• Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels..  9:-. 2018
• Honey bee Royalactin unlocks conserved pluripotency pathway in mammals..  9:-. 2018
• SYK kinase mediates brown fat differentiation and activation..  8:-. 2017
• Label-free automated three-dimensional imaging of whole organs by microtomy-assisted photoacoustic microscopy..  8:-. 2017
• Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass..  8:-. 2017
• Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus..  8:-. 2017
• Large meta-analysis of genome-wide association studies identifies five loci for lean body mass..  8:-. 2017
• Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness..  -. 2017
• Cellular senescence drives age-dependent hepatic steatosis..  -. 2017
• Genetic architecture of epigenetic and neuronal ageing rates in human brain regions..  -. 2017
• Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge..  -. 2017
• Caloric restriction improves health and survival of rhesus monkeys..  -. 2017
• Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss..  -. 2017
• Macrophage-released ADAMTS1 promotes muscle stem cell activation..  8:-. 2017
• Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology..  -. 2016
• Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1..  -. 2016
• Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum..  -. 2016
• New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk..  -. 2016
• Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects..  -. 2016
• Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy..  -. 2015
• Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels..  -. 2015
• Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility..  -. 2015
• Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder..  -. 2014
• A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases..  -. 2013
• Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice..  -. 2013
• Sulfhydration mediates neuroprotective actions of parkin..  -. 2013
• The TSC-mTOR pathway regulates macrophage polarization..  -. 2013
• Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo..  -. 2012
• High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform 2023
• Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells 2020

Identity

International Standard Serial Number (ISSN)

• 2041-1723