Neurobiology of aging
Journal
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Overview
publication venue for
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A neural implementation of cognitive reserve: Insights from a longitudinal fMRI study of set-switching in aging..
76-83.
2024
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Hypothalamic MRI-derived microstructure is associated with neurocognitive aging in humans..
102-112.
2024
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The relationship between cortical thickness and white matter hyperintensities in mid to late life..
129-139.
2024
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Cognitive reserve proxies are associated with age-related cognitive decline - Not age-related gait speed decline..
46-54.
2024
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Reserve, resilience and maintenance of episodic memory and other cognitive functions in aging..
60-69.
2024
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Elevated protease-activated receptor 4 (PAR4) gene expression in Alzheimer's disease predicts cognitive decline..
93-101.
2024
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Childhood engagement in cognitively stimulating activities moderates relationships between brain structure and cognitive function in adulthood..
36-44.
2024
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Personality traits and cognitive reserve-High openness benefits cognition in the presence of age-related brain changes..
38-46.
2024
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Perivascular space burden interacts with APOE-ε4 status on cognition in older adults..
1-8.
2024
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Changes in an in-vivo classifier of ARTerioloSclerosis (ARTS) with simultaneous change in cognition for older African Americans..
21-27.
2023
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In vivo tau is associated with change in memory and processing speed, but not reasoning, in cognitively unimpaired older adults..
28-38.
2023
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Effect of short-term androgen supplementation on cognitive performance in older male rhesus macaques..
246-249.
2023
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Moderating role of physical activity on hippocampal iron deposition and memory outcomes in typically aging older adults..
124-131.
2023
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Extracellular matrix proteoglycans support aged hippocampus networks: a potential cellular-level mechanism of brain reserve..
52-58.
2023
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Amyloid and tau pathology are associated with cerebral blood flow in a mixed sample of nondemented older adults with and without vascular risk factors for Alzheimer's disease..
103-113.
2023
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Sleep quality and sleep duration predict brain microstructure among community-dwelling older adults..
90-97.
2023
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Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease..
25-33.
2023
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Whole blood transcript and protein abundance of the vascular endothelial growth factor family relate to cognitive performance..
11-17.
2023
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A framework for concepts of reserve and resilience in aging..
100-103.
2022
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Enlarged perivascular space burden associations with arterial stiffness and cognition..
85-97.
2022
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Plasma neurofilament light as blood marker for poor brain white matter integrity among middle-aged urban adults..
52-63.
2022
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Biological correlates of elevated soluble TREM2 in cerebrospinal fluid..
88-98.
2022
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RNASE6 is a novel modifier of APOE-ε4 effects on cognition..
66-76.
2022
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Predicting future cognitive decline from non-brain and multimodal brain imaging data in healthy and pathological aging..
55-65.
2022
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Cerebrovascular response to exercise interacts with individual genotype and amyloid-beta deposition to influence response inhibition with aging..
15-26.
2022
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Cognitively stimulating environments and cognitive reserve: the case of personal social networks..
197-203.
2022
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Beta-amyloid moderates the relationship between cortical thickness and attentional control in middle- and older-aged adults..
181-190.
2022
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Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia..
35-43.
2021
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Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes..
95-106.
2021
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Brain-predicted age difference is associated with cognitive processing in later-life..
195-203.
2021
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Relationship of APOE, age at onset, amyloid and clinical phenotype in Alzheimer disease..
90-98.
2021
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Red cell distribution width, anemia and their associations with white matter integrity among middle-aged urban adults..
229-240.
2021
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Age-dependent relationship of cardiorespiratory fitness and white matter integrity..
48-56.
2021
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Sex differences in in vivo tau neuropathology in a multiethnic sample of late middle-aged adults..
109-116.
2021
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Sleep, rest-activity rhythms and aging: a complex web in Alzheimer's disease?.
102-103.
2021
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Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25..
64-72.
2021
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KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers..
123-129.
2021
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Education and age-related differences in cortical thickness and volume across the lifespan..
102-110.
2020
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Cerebrospinal fluid Aβ42 moderates the relationship between brain functional network dynamics and cognitive intraindividual variability..
116-123.
2020
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Metabolic syndrome and its components in relation to in vivo brain amyloid and neurodegeneration in late middle age..
89-96.
2020
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Spatiotemporal relationship between subthreshold amyloid accumulation and aerobic glycolysis in the human brain..
165-175.
2020
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Evaluating resting-state BOLD variability in relation to biomarkers of preclinical Alzheimer's disease..
233-245.
2020
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MicroRNA predicts cognitive performance in healthy older adults..
186-194.
2020
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Relationship between neural functional connectivity and memory performance in age-related macular degeneration..
176-185.
2020
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Free-water metrics in medial temporal lobe white matter tract projections relate to longitudinal cognitive decline..
15-23.
2020
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Optimized prediction of cognition based on brain morphometry across the adult life span..
16-24.
2020
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Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults..
124-130.
2020
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Estimating brain age based on a uniform healthy population with deep learning and structural magnetic resonance imaging..
15-25.
2020
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Long-standing multiple sclerosis neurodegeneration: volumetric magnetic resonance imaging comparison to Parkinson's disease, mild cognitive impairment, Alzheimer's disease, and elderly healthy controls..
84-92.
2020
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Profile of pathogenic proteins in total circulating extracellular vesicles in mild cognitive impairment and during the progression of Alzheimer's disease..
102-111.
2019
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Functional connectivity among brain regions affected in Alzheimer's disease is associated with CSF TNF-α in APOE4 carriers..
112-122.
2019
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Brain reserve, cognitive reserve, compensation, and maintenance: operationalization, validity, and mechanisms of cognitive resilience..
124-129.
2019
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What are the later life contributions to reserve, resilience, and compensation?.
140-144.
2019
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Microglial activation, but not tau pathology, is independently associated with amyloid positivity and memory impairment..
11-21.
2019
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The relationship between white matter hyperintensities and cognitive reference abilities across the life span..
31-41.
2019
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Associations between modifiable risk factors and white matter of the aging brain: insights from diffusion tensor imaging studies..
56-70.
2019
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Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid..
178-185.
2019
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Cognitive aging is not created equally: differentiating unique cognitive phenotypes in "normal" adults..
13-19.
2019
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Seizures as an early symptom of autosomal dominant Alzheimer's disease..
18-23.
2018
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Genetic analysis of neurodegenerative diseases in a pathology cohort..
214.e1-214.e9.
2018
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In vivo hippocampal subfield shape related to TDP-43, amyloid beta, and tau pathologies..
171-181.
2018
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Sex-dependent effect of the BDNF Val66Met polymorphism on executive functioning and processing speed in older adults: evidence from the health ABC study..
161-170.
2018
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Modeling white matter tract integrity in aging with diffusional kurtosis imaging..
265-275.
2018
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Neurofilament relates to white matter microstructure in older adults..
233-241.
2018
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Association of telomere length with general cognitive trajectories: a meta-analysis of four prospective cohort studies..
111-116.
2018
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Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults..
68-75.
2018
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APOE genotype modifies the association between central arterial stiffening and cognition in older adults..
120-127.
2018
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Language processing in age-related macular degeneration associated with unique functional connectivity signatures in the right hemisphere..
65-74.
2017
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Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults..
64-71.
2017
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Association of anti-inflammatory cytokine IL10 polymorphisms with motoric cognitive risk syndrome in an Ashkenazi Jewish population..
238.e1-238.e8.
2017
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Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults..
153-161.
2017
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Neuropsychological measures that detect early impairment and decline in preclinical Alzheimer disease..
25-32.
2017
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Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples..
83-92.
2017
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Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2..
193.e17-193.e25.
2017
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Alzheimer's-related cortical atrophy is associated with postoperative delirium severity in persons without dementia..
55-63.
2017
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Retinal thinning is uniquely associated with medial temporal lobe atrophy in neurologically normal older adults..
141-147.
2016
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Cognitive reserve moderates the association between functional network anti-correlations and memory in MCI..
152-162.
2016
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Malignant progression in parietal-dominant atrophy subtype of Alzheimer's disease occurs independent of onset age..
149-156.
2016
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Widespread white matter and conduction defects in PSEN1-related spastic paraparesis..
201-209.
2016
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Discrepancies between fluid and crystallized ability in healthy adults: a behavioral marker of preclinical Alzheimer's disease..
68-75.
2016
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Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models..
159-172.
2016
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Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease..
177-88.
2016
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Differences between chronological and brain age are related to education and self-reported physical activity..
138-144.
2016
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The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume..
68-77.
2016
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Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring..
61-67.
2015
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Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome..
151-163.
2015
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Aβ-related hyperactivation in frontoparietal control regions in cognitively normal elderly..
36:3247-3254.
2015
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Breadth and age-dependency of relations between cortical thickness and cognition..
36:3020-3028.
2015
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Trajectories of peripheral interleukin-6, structure of the hippocampus, and cognitive impairment over 14 years in older adults..
36:3038-3044.
2015
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NLRP3 inflammasome activation by mitochondrial reactive oxygen species plays a key role in long-term cognitive impairment induced by paraquat exposure..
36:2533-43.
2015
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Stroke risk interacts with Alzheimer's disease biomarkers on brain aging outcomes..
36:2501-8.
2015
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Serum IGF-BP2 strongly moderates age's effect on cognition: a MIMIC analysis..
36:2232-2240.
2015
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Brain atrophy and white-matter hyperintensities are not significantly associated with incidence and severity of postoperative delirium in older persons without dementia..
36:2122-9.
2015
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Task-evoked fMRI changes in attention networks are associated with preclinical Alzheimer's disease biomarkers..
36:1771-9.
2015
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Declines in inflammation predict greater white matter microstructure in older adults..
36:948-54.
2014
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Increased free water in the substantia nigra of Parkinson's disease: a single-site and multi-site study..
36:1097-104.
2014
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Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease..
35:2883.e3-2883.e10.
2014
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Reconsidering harbingers of dementia: progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence..
36:27-32.
2014
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Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits..
36:265-72.
2014
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Trajectories of inflammatory markers and cognitive decline over 10 years..
35:2785-2790.
2014
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Amyloid-β diurnal pattern: possible role of sleep in Alzheimer's disease pathogenesis..
S29-34.
2014
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Dietary and lifestyle guidelines for the prevention of Alzheimer's disease..
S74-8.
2014
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Physical activity, body mass index, and brain atrophy in Alzheimer's disease..
36 Suppl 1:S194-S202.
2014
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Amyloid burden and neural function in people at risk for Alzheimer's Disease..
35:576-84.
2013
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Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models..
34:1581-8.
2013
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Functional connectivity and graph theory in preclinical Alzheimer's disease..
35:757-68.
2013
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Missense variant in TREML2 protects against Alzheimer's disease..
35:1510.e19-26.
2013
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FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion..
34:1516.e17-9.
2012
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Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals..
34:822-31.
2012
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Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease..
34:1-12.
2012
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Estimating sample sizes for predementia Alzheimer's trials based on the Alzheimer's Disease Neuroimaging Initiative..
34:62-72.
2012
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Toward a multifactorial model of Alzheimer disease..
33:2262-71.
2012
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Localized hippocampus measures are associated with Alzheimer pathology and cognition independent of total hippocampal volume..
33:1124.e31-41.
2011
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Potential of functional MRI as a biomarker in early Alzheimer's disease..
32 Suppl 1:S37-43.
2011
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Hippocampal and ventricular changes in Parkinson's disease mild cognitive impairment..
33:2113-24.
2011
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A genome-wide association study of aging..
32:2109.e15-28.
2011
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Age and amyloid-related alterations in default network habituation to stimulus repetition..
33:1237-52.
2011
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CSF biomarkers for Alzheimer's disease: current utility and potential future use..
32 Suppl 1:S4-9.
2011
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White matter lesions and brain gray matter volume in cognitively normal elders..
33:834.e7-16.
2011
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Effects of ApoE4 and maternal history of dementia on hippocampal atrophy..
33:856-66.
2010
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3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects..
31:1284-303.
2010
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Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series..
33:426.e13-21.
2010
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Obesity is linked with lower brain volume in 700 AD and MCI patients..
31:1326-39.
2010
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Telomere length and cognitive function in community-dwelling elders: findings from the Health ABC Study..
32:2055-60.
2009
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White matter hyperintensities and cognition: testing the reserve hypothesis..
32:1588-98.
2009
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Age-related changes in glutamate release in the CA3 and dentate gyrus of the rat hippocampus..
32:811-20.
2009
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Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal..
31:1077-88.
2008
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Cardiovascular risk and memory in non-demented elderly women..
31:1250-3.
2008
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Rate of entorhinal and hippocampal atrophy in incipient and mild AD: relation to memory function..
31:1089-98.
2008
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Serum leptin level and cognition in the elderly: Findings from the Health ABC Study..
30:1483-9.
2008
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Apolipoprotein E mediates sulfatide depletion in animal models of Alzheimer's disease..
31:1188-96.
2008
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The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease..
30:672-81.
2007
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Protection against beta-amyloid induced abnormal synaptic function and cell death by Ginkgolide J..
30:257-65.
2007
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A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice..
29:836-47.
2007
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Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death..
28:1709-17.
2006
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Age-related changes in brain activation during a delayed item recognition task..
28:784-98.
2006
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Structural MRI covariance patterns associated with normal aging and neuropsychological functioning..
28:284-95.
2006
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Verbal paired-associate learning by APOE genotype in non-demented older adults: fMRI evidence of a right hemispheric compensatory response..
28:238-47.
2006
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Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?.
27:524-9.
2005
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Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment..
27:394-401.
2005
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Hippocampal and neocortical activation during repetitive encoding in older persons..
27:173-82.
2005
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Abeta deposition is associated with enhanced cortical alpha-synuclein lesions in Lewy body diseases..
26:1183-92.
2004
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Divergence of the apoptotic pathways induced by 4-hydroxynonenal and amyloid beta-protein..
25:1057-66.
2004
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Obesity enhances verbal memory in postmenopausal women with Down syndrome..
25:159-66.
2004
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Immune responses against Abeta1-42 in HLA class II transgenic mice: implications for Abeta1-42 immune-mediated therapies..
24:969-76.
2003
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Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice..
24:245-58.
2003
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Use of YFP to study amyloid-beta associated neurite alterations in live brain slices..
24:1071-7.
2003
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Abeta conformational change is central to Alzheimer's disease..
23:1085-8.
2002
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Open peer commentary regarding Abeta immunization and CNS inflammation by Pasinetti et al..
23:671-4; discussion 683-4.
2002
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Memory performance in healthy elderly without Alzheimer's disease: effects of time and apolipoprotein-E..
22:683-9.
2001
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Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition..
22:721-7.
2001
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NGF expression in the aged rat pineal gland does not correlate with loss of sympathetic axonal branches and varicosities..
20:685-93.
1999
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Neurotrophin receptor and tyrosine hydroxylase gene expression in aged sympathetic neurons..
18:67-79.
1997
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Synthetic amyloid beta-protein fails to produce specific neurotoxicity in monkey cerebral cortex..
13:561-7.
1992
Identity
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