Selected Publications
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article
- Bone health in women with hidradenitis suppurativa: addressing osteoporosis risks and management options.. International journal of women's dermatology. 12:-. 2026
- Comments to the "Letter to the Editor" for the manuscript titled "Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease".. Brain pathology (Zurich, Switzerland). -. 2026
- Common Medical Comorbidities, Demographic Factors and Levels of Plasma Biomarkers of Alzheimer's Disease and Neurodegeneration in Black/African American Older Adults.. Biomolecules. 16. 2026
- Inflammasomes in glioblastoma.. Journal of neuroinflammation. 23. 2026
- Interleukin-18 as a Potential Biomarker for Radiotherapy-Related Pain in Breast Cancer: Implications for Personalized Pain Management.. Cancers. 18. 2026
- Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease.. Brain pathology (Zurich, Switzerland). -. 2026
- Feasibility Study on Inflammasome Proteins as Biomarkers in the Cerebrospinal Fluid of Pediatric Patients with Hydrocephalus Due to Intraventricular Hemorrhage.. Biomolecules. 16. 2025
- Potential Role of Serum Cytokines and Chemokines as Biomarkers of Injury Severity and Functional Outcomes Following Pediatric Traumatic Brain Injury.. Cells. 15. 2025
- Neuronal inflammasomes: balancing immunity, neuroinflammation, and homeostasis.. Trends in immunology. 47:375-396. 2025
- Association of serum inflammasome proteins and pediatric traumatic brain injury severity.. Pediatric research. 99:1494-1503. 2025
- Lung-Brain Axis-Generated Inflammatory Biomarkers in Traumatic Brain Injury and Acute Respiratory Distress Syndrome: Role of Mechanical Ventilation/Stress.. Advances in biomarker sciences and technology. 238-247. 2025
- Predictive Value of Nervous Cell Injury Biomarkers in Moderate-to-Severe Traumatic Brain Injury: A Network Meta-Analysis.. Neurology. 105:-. 2025
- Effects of Acute Probenecid Administration on Histopathological and Functional Outcomes after Spinal Cord Injury in Rats.. Neurotrauma reports. 6:425-434. 2025
- The impact of innate immunity and epigenetics in the pathogenesis of hidradenitis suppurativa.. Frontiers in immunology. -. 2025
- Effects of iron accumulation and its chelation on oxidative stress in intracortical implants.. Acta biomaterialia. 703-723. 2025
- IC100 blocks inflammasome activation induced by α-synuclein aggregates and ASC specks.. NPJ Parkinson's disease. 11:-. 2025
- Acute Neurovascular Inflammatory Profile in Patients with Aneurysmal Subarachnoid Hemorrhage.. Biomolecules. 15. 2025
- Stool-derived extracellular vesicles increase inflammasome signaling and regulate the gut-brain axis after stroke in Alzheimer's disease transgenic mice.. Experimental neurology. -. 2025
- Gasdermin-D Genetic Knockout Reduces Inflammasome-Induced Disruption of the Gut-Brain Axis After Traumatic Brain Injury.. International journal of molecular sciences. 26. 2025
- Effects of Space Flight on Inflammasome Activation in the Brain of Mice.. Cells. 14. 2025
- 3,3'-Diindolylmethane improves pathology and neurological outcome following traumatic brain injury.. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 22:-. 2025
- Comparison of Methods of Detecting IL-1β in the Blood of Alzheimer's Disease Subjects.. International journal of molecular sciences. 26. 2025
- Catecholamine-Induced Inflammasome Activation in the Heart Following Photothrombotic Stroke.. Translational stroke research. 16:1317-1330. 2024
- Increased inflammasome protein expression identified in microglia from postmortem brains with schizophrenia.. Journal of neuropathology and experimental neurology. 83:951-966. 2024
- Extracellular Vesicle ASC: A Novel Mediator for Lung-Brain Axis in Preterm Brain Injury.. American journal of respiratory cell and molecular biology. 71:464-480. 2024
- Challenges in advancing Schwann cell transplantation for spinal cord injury repair.. Cytotherapy. 27:36-50. 2024
- Inflammasome Proteins Are Reliable Biomarkers of the Inflammatory Response in Aneurysmal Subarachnoid Hemorrhage.. Cells. 13. 2024
- The Inflammasome Adaptor Protein ASC in Plasma as a Biomarker of Early Cognitive Changes.. International journal of molecular sciences. 25. 2024
- Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease.. Neural regeneration research. 20:1644-1664. 2024
- IC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice.. Angiogenesis. 27:423-440. 2024
- Extracellular vesicles mediate inflammasome signaling in the brain and heart of Alzheimer's disease mice.. Frontiers in molecular neuroscience. -. 2024
- post mortem. Alzheimer's & dementia (New York, N. Y.). 10:-. 2024
- The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes.. Cells. 12. 2023
- Prognostic and Diagnostic Utility of Serum Biomarkers in Pediatric Traumatic Brain Injury.. Journal of neurotrauma. 41:106-122. 2023
- Neural-Cardiac Inflammasome Axis after Traumatic Brain Injury.. Pharmaceuticals (Basel, Switzerland). 16. 2023
- Utility of Brain Injury Biomarkers in Children With Congenital Heart Disease Undergoing Cardiac Surgery.. Pediatric neurology. 44-53. 2023
- Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson's Disease.. Pharmaceuticals (Basel, Switzerland). 16. 2023
- Sex Differences in the Inflammatory Profile in the Brain of Young and Aged Mice.. Cells. 12. 2023
- Importance of timing optimization for closed-loop applications of vagus nerve stimulation.. Bioelectronic medicine. 9:-. 2023
- Inflammasome signaling proteins as biomarkers of COVID-19.. Frontiers in immunology. -. 2023
- Activation of inflammasomes and their effects on neuroinflammation at the microelectrode-tissue interface in intracortical implants.. Biomaterials. -. 2023
- Genetic Predisposition to Alzheimer's Disease Alters Inflammasome Activity After Traumatic Brain Injury.. Translational research : the journal of laboratory and clinical medicine. 66-77. 2023
- Methods to Study Inflammasome Activation in the Central Nervous System: Immunoblotting and Immunohistochemistry.. Methods in molecular biology (Clifton, N.J.). 223-238. 2023
- Identification of inflammasome signaling proteins in neurons and microglia in early and intermediate stages of Alzheimer's disease.. Brain pathology (Zurich, Switzerland). 33:-. 2022
- Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview.. Neuroscience and biobehavioral reviews. -. 2022
- Intraocular inflammasome signalling in failed corneal transplants.. Eye (London, England). 37:787-789. 2022
- Inflammasome activation in traumatic brain injury and Alzheimer's disease.. Translational research : the journal of laboratory and clinical medicine. 1-12. 2022
- The inflammasome pathway: A key player in ocular surface and anterior segment diseases.. Survey of ophthalmology. 68:280-289. 2022
- MECHANISM OF ACTION OF IC 100, A HUMANIZED IgG4 MONOCLONAL ANTIBODY TARGETING APOPTOSIS-ASSOCIATED SPECK-LIKE STAINING PROTEIN CONTAINING A CASPASE RECRUITMENT DOMAIN (ASC).. Translational research : the journal of laboratory and clinical medicine. 27-40. 2022
- Cohort study on the differential expression of inflammatory and angiogenic factors in thrombi, cerebral and peripheral plasma following acute large vessel occlusion stroke.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 42:-. 2022
- Inflammatory Biomarkers of Traumatic Brain Injury.. Pharmaceuticals (Basel, Switzerland). 15. 2022
- Renal and Inflammatory Proteins as Biomarkers of Diabetic Kidney Disease and Lupus Nephritis.. Oxidative medicine and cellular longevity. -. 2022
- Role of Caspase-1 as a Biomarker of Ocular Surface Damage.. American journal of ophthalmology. 74-83. 2022
- The Role of Non-canonical and Canonical Inflammasomes in Inflammaging.. Frontiers in molecular neuroscience. -. 2022
- Serum Caspase-1 as an Independent Prognostic Factor in Traumatic Brain Injured Patients.. Neurocritical care. 36:527-535. 2021
- Age-Dependent Microglial Response to Systemic Infection.. Cells. 10. 2021
- Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats.. Scientific reports. 11:-. 2021
- Tumor necrosis factor-alpha and interferon-gamma induce inflammasome-mediated corneal endothelial cell death.. Experimental eye research. -. 2021
- Netosis and Inflammasomes in Large Vessel Occlusion Thrombi.. Frontiers in pharmacology. -. 2021
- Inflammasome Proteins as Inflammatory Biomarkers of Age-Related Macular Degeneration.. Translational vision science & technology. 9:-. 2020
- Inflammasome Proteins as Inflammatory Biomarkers of Age-Related Macular Degeneration.. Translational vision science & technology. 9:-. 2020
- ASC, IL-18 and Galectin-3 as Biomarkers of Non-Alcoholic Steatohepatitis: A Proof of Concept Study.. International journal of molecular sciences. 21. 2020
- The Inflammasome in Times of COVID-19.. Frontiers in immunology. -. 2020
- The Inflammasome in Times of COVID-19.. Frontiers in immunology. -. 2020
- Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets.. Journal of neuroinflammation. 17:-. 2020
- Enoxaparin Attenuates Acute Lung Injury and Inflammasome Activation after Traumatic Brain Injury.. Journal of neurotrauma. 38:646-654. 2020
- The Inflammasome Signaling Proteins ASC and IL-18 as Biomarkers of Psoriasis.. Frontiers in pharmacology. -. 2020
- The Inflammasome Adaptor Protein ASC in Mild Cognitive Impairment and Alzheimer's Disease.. International journal of molecular sciences. 21. 2020
- IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis.. Journal of neuroinflammation. 17:-. 2020
- Levels of caspase-1 in cerebrospinal fluid of patients with traumatic brain injury: correlation with intracranial pressure and outcome.. Journal of neurosurgery. 134:1644-1649. 2020
- The Inflammasome in Reproductive Biology: A Promising Target for Novel Therapies.. Frontiers in endocrinology. -. 2020
- Oligodendrocytes modulate the immune-inflammatory response in EAE via TNFR2 signaling.. Brain, behavior, and immunity. 132-146. 2019
- Neural-respiratory inflammasome axis in traumatic brain injury.. Experimental neurology. -. 2019
- Caspase-1 Inhibition Attenuates Hyperoxia-induced Lung and Brain Injury in Neonatal Mice.. American journal of respiratory cell and molecular biology. 61:341-354. 2019
- Estrogen preconditioning: A promising strategy to reduce inflammation in the ischemic brain.. Conditioning medicine. 2:106-113. 2019
- The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury.. Journal of neuroinflammation. 16:-. 2019
- Human Lung Cell Pyroptosis Following Traumatic Brain Injury.. Cells. 8. 2019
- Carbon monoxide releasing molecule-3 inhibits inflammasome activation: A potential therapy for spinal cord injury.. EBioMedicine. 17-18. 2019
- Inflammasome proteins as biomarkers of traumatic brain injury.. PloS one. 13:-. 2018
- Sexual dimorphism in inflammasome-containing extracellular vesicles and the regulation of innate immunity in the brain of reproductive senescent females.. Neurochemistry international. 29-37. 2018
- Contribution of the inflammasome to inflammaging.. Journal of inflammation (London, England). -. 2018
- Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke.. Frontiers in molecular neuroscience. -. 2018
- Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response.. Neuron. 99:914-924.e3. 2018
- Traumatic Brain Injury-Induced Acute Lung Injury: Evidence for Activation and Inhibition of a Neural-Respiratory-Inflammasome Axis.. Journal of neurotrauma. 35:2067-2076. 2018
- Nicotine Alters Estrogen Receptor-Beta-Regulated Inflammasome Activity and Exacerbates Ischemic Brain Damage in Female Rats.. International journal of molecular sciences. 19. 2018
- Microglial Inflammasome Activation in Penetrating Ballistic-Like Brain Injury.. Journal of neurotrauma. 35:1681-1693. 2018
- Inflammasome Proteins As Biomarkers of Multiple Sclerosis.. Frontiers in neurology. -. 2018
- Inhibition of Rac1 Signaling Downregulates Inflammasome Activation and Attenuates Lung Injury in Neonatal Rats Exposed to Hyperoxia.. Neonatology. 111:280-288. 2016
- A computational model for investigating the effects of changes in bioavailability of insulin-like growth factor-1 on the homeostasis of the intervertebral disc.. Computers in biology and medicine. 126-137. 2016
- Acidification changes affect the inflammasome in human nucleus pulposus cells.. Journal of inflammation (London, England). 13:-. 2016
- Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice.. The Journal of experimental medicine. 213:929-49. 2016
- Estrogen receptor beta signaling alters cellular inflammasomes activity after global cerebral ischemia in reproductively senescence female rats.. Journal of neurochemistry. 136:492-6. 2015
- RIG-I contributes to the innate immune response after cerebral ischemia.. Journal of inflammation (London, England). -. 2015
- RIG-I contributes to the innate immune response after cerebral ischemia.. Journal of inflammation (London, England). -. 2015
- Effects of Tobacco Smoking on the Degeneration of the Intervertebral Disc: A Finite Element Study.. PloS one. 10:-. 2015
- Therapeutics targeting the inflammasome after central nervous system injury.. Translational research : the journal of laboratory and clinical medicine. 167:35-45. 2015
- Exosome-mediated inflammasome signaling after central nervous system injury.. Journal of neurochemistry. 136 Suppl 1:39-48. 2015
- Mincle signaling in the innate immune response after traumatic brain injury.. Journal of neurotrauma. 32:228-36. 2014
- Mincle signaling in the innate immune response after traumatic brain injury.. Journal of neurotrauma. 32:228-36. 2014
- A computational analysis on the implications of age-related changes in the expression of cellular signals on the role of IGF-1 in intervertebral disc homeostasis.. Journal of biomechanics. 48:332-9. 2014
- Neutralization of ASC improves sperm motility in men with spinal cord injury.. Human reproduction (Oxford, England). 29:2368-73. 2014
- Pattern recognition receptors and central nervous system repair.. Experimental neurology. 5-16. 2014
- The inflammasome pyrin contributes to pertussis toxin-induced IL-1β synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.. PLoS pathogens. 10:-. 2014
- RIG-1 receptor expression in the pathology of Alzheimer's disease.. Journal of neuroinflammation. -. 2014
- Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 34:369-75. 2014
- Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 34:621-9. 2014
- Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load.. PloS one. 8:-. 2013
- Human astrocytes express a novel NLRP2 inflammasome.. Glia. 61:1113-21. 2013
- Inflammasome proteins in cerebrospinal fluid of brain-injured patients as biomarkers of functional outcome: clinical article.. Journal of neurosurgery. 117:1119-25. 2012
- Involvement of the inflammasome in abnormal semen quality of men with spinal cord injury.. Fertility and sterility. 99:118-124.e2. 2012
- Effects of therapeutic hypothermia on inflammasome signaling after traumatic brain injury.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 32:1939-47. 2012
- Caspase-1 level is higher in the scalp in androgenetic alopecia.. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 38:1033-9. 2012
- P2X4 receptors influence inflammasome activation after spinal cord injury.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32:3058-66. 2012
- Astrogliosis involves activation of retinoic acid-inducible gene-like signaling in the innate immune response after spinal cord injury.. Glia. 60:414-21. 2011
- Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats.. BMC neuroscience. -. 2011
- Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain.. Brain research. 23-34. 2011
- In vivo electroporation and non-protein based screening assays to identify antibodies against native protein conformations.. Hybridoma (2005). 30:409-18. 2011
- Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury.. Journal of neurotrauma. 29:936-45. 2011
- Functional recovery after peripheral nerve injury is dependent on the pro-inflammatory cytokines IL-1β and TNF: implications for neuropathic pain.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31:12533-42. 2011
- Oligodendrocyte vulnerability following traumatic brain injury in rats.. Neuroscience letters. 499:143-8. 2011
- Oligodendrocyte vulnerability following traumatic brain injury in rats.. Neuroscience letters. 499:143-8. 2011
- OLIGODENDROCYTE VULNERABILITY FOLLOWING TRAUMATIC BRAIN INJURY IN RATS: EFFECT OF MODERATE HYPOTHERMIA.. Therapeutic hypothermia and temperature management. 1:43-51. 2011
- Neuroprotective effects of bone morphogenetic protein 7 (BMP7) treatment after spinal cord injury.. Neuroscience letters. 465:226-9. 2009
- Alterations in blood-brain barrier permeability to large and small molecules and leukocyte accumulation after traumatic brain injury: effects of post-traumatic hypothermia.. Journal of neurotrauma. 26:1123-34. 2009
- The pannexin 1 channel activates the inflammasome in neurons and astrocytes.. The Journal of biological chemistry. 284:18143-51. 2009
- Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 29:1251-61. 2009
- Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 29:534-44. 2008
- A molecular platform in neurons regulates inflammation after spinal cord injury.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28:3404-14. 2008
- Therapeutic hypothermia modulates TNFR1 signaling in the traumatized brain via early transient activation of the JNK pathway and suppression of XIAP cleavage.. The European journal of neuroscience. 24:2283-90. 2006