Publications in VIVO

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Co-investigator Network

Joseph Hippensteel, MD MS

Person

Positions

Assistant Professor, University of Colorado Anschutz Medical Campus

Location

Aurora, Colorado 80045

USA

My scientific work focuses on the intersection of critical illness and cognition. I am particularly interested in the role of the endothelial glycocalyx and its constituents in the cognitive effects commonly associated with critical illness syndromes like sepsis and acute respiratory distress sydrome (ARDS).

Clinical Disciplines

Geographic Focus

Colorado State or Province

GEMSSTAR awardee

Publications
Research
Other
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Selected Publications

article
1. Tackling Brain and Muscle Dysfunction in Acute Respiratory Distress Syndrome Survivors: NHLBI Workshop Report.. American journal of respiratory and critical care medicine. 209:1304-1313. 2024
2. A New Era in Critical Care Trials: Linking ICU Practice to Long-Term Outcomes.. American journal of respiratory and critical care medicine. 209:782-784. 2024
3. A role for decorin in improving motor deficits after traumatic brain injury.. Matrix biology : journal of the International Society for Matrix Biology. 88-99. 2023
4. Endothelial Glycocalyx Degradation Patterns in Sepsis-Associated Pediatric Acute Respiratory Distress Syndrome: A Single Center Retrospective Observational Study.. Journal of intensive care medicine. 39:-. 2023
5. Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 19:2150-2174. 2023
6. Predictors of adverse outcomes in aged patients critically ill with COVID-19: a retrospective study.. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 71:-. 2023
7. Proteoglycans and Glycosaminoglycans in Central Nervous System Injury.. American journal of physiology. Cell physiology. 323:C46-C55. 2022
8. Endothelial glycocalyx degradation during sepsis: Causes and consequences.. Matrix biology plus. -. 2021
9. Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19.. Medical hypotheses. -. 2020
10. Prevalence of venous thromboembolism in critically ill patients with COVID-19.. British journal of haematology. 190:e134-e137. 2020
11. Heparin as a therapy for COVID-19: current evidence and future possibilities.. American journal of physiology. Lung cellular and molecular physiology. 319:L211-L217. 2020
12. Circulating heparan sulfate fragments mediate septic cognitive dysfunction.. The Journal of clinical investigation. 2019
13. Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions. Proceedings of the National Academy of Sciences. 2019
14. Staphylococcus aureus adhesion in endovascular infections is controlled by the ArlRS–MgrA signaling cascade. PLOS Pathogens. 2019